Portsmouth, Ohio to St. Charles, Maryland: Road Trip Guide & Distance

How far is Portsmouth, Ohio from St. Charles, Maryland?

The distance from Portsmouth, Ohio to St. Charles, Maryland is 327.6 miles (527.3 km) as the crow flies. St. Charles, Maryland is located E of Portsmouth, Ohio. By car, the driving distance is approximately 393.2 miles, taking about 7h 55min. A direct flight would take roughly 1h 10min. Both are located in United States — Portsmouth, Ohio in Ohio and St. Charles, Maryland in Maryland.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Portsmouth, Ohio and St. Charles, Maryland. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.