Portsmouth, Ohio to Saint Charles, Maryland: Road Trip Guide & Distance

How far is Portsmouth, Ohio from Saint Charles, Maryland?

The distance from Portsmouth, Ohio to Saint Charles, Maryland is 326.9 miles (526.1 km) as the crow flies. Saint Charles, Maryland is located E of Portsmouth, Ohio. By car, the driving distance is approximately 392.3 miles, taking about 7h 53min. A direct flight would take roughly 1h 9min. Both are located in United States — Portsmouth, Ohio in Ohio and Saint Charles, Maryland in Maryland.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Portsmouth, Ohio and Saint Charles, Maryland. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.