Poplar Bluff to Tupelo: Road Trip Guide & Distance

How far is Poplar Bluff from Tupelo?

The distance from Poplar Bluff to Tupelo is 197 miles (317.1 km) as the crow flies. Tupelo is located SSE of Poplar Bluff. By car, the driving distance is approximately 246.3 miles, taking about 4h 57min. A direct flight would take roughly 54min. Both are located in United States — Poplar Bluff in Missouri and Tupelo in Mississippi.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Poplar Bluff and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.