Panama City Beach to Siesta Key: Road Trip Guide & Distance

How far is Panama City Beach from Siesta Key?

The distance from Panama City Beach to Siesta Key is 281.7 miles (453.4 km) as the crow flies. Siesta Key is located SE of Panama City Beach. By car, the driving distance is approximately 352.2 miles, taking about 7h 5min. A direct flight would take roughly 1h 4min. Both are located in United States.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Panama City Beach and Siesta Key. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.