Palmdale to Palo Alto: Road Trip Guide & Distance

How far is Palmdale from Palo Alto?

The distance from Palmdale to Palo Alto is 299.6 miles (482.1 km) as the crow flies. Palo Alto is located NW of Palmdale. By car, the driving distance is approximately 374.4 miles, taking about 7h 32min. A direct flight would take roughly 1h 6min. Both are located in United States.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Palmdale and Palo Alto. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.