Oxford, Ohio to Winston-Salem: Road Trip Guide & Distance

How far is Oxford, Ohio from Winston-Salem?

The distance from Oxford, Ohio to Winston-Salem is 340.2 miles (547.5 km) as the crow flies. Winston-Salem is located SE of Oxford, Ohio. By car, the driving distance is approximately 408.2 miles, taking about 8h 13min. A direct flight would take roughly 1h 11min. Both are located in United States — Oxford, Ohio in Ohio and Winston-Salem in North Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Oxford, Ohio and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.