Owensboro to Oxford, Mississippi: Road Trip Guide & Distance

How far is Owensboro from Oxford, Mississippi?

The distance from Owensboro to Oxford, Mississippi is 271 miles (436.2 km) as the crow flies. Oxford, Mississippi is located SSW of Owensboro. By car, the driving distance is approximately 338.8 miles, taking about 6h 49min. A direct flight would take roughly 1h 3min. Both are located in United States — Owensboro in Kentucky and Oxford, Mississippi in Mississippi.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Owensboro and Oxford, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.