Orlando to Winston-Salem: Road Trip Guide & Distance

How far is Orlando from Winston-Salem?

The distance from Orlando to Winston-Salem is 526.6 miles (847.5 km) as the crow flies. Winston-Salem is located N of Orlando. By car, the driving distance is approximately 631.9 miles, taking about 12h 43min. A direct flight would take roughly 1h 34min. Both are located in United States — Orlando in Florida and Winston-Salem in North Carolina.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Heading North for this distance usually means noticeable weather changes. Make sure to check the forecast for your destination before hitting the road.

Coordinates come from public place data for Orlando and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.