Opelousas to Wylie: Road Trip Guide & Distance

How far is Opelousas from Wylie?

The distance from Opelousas to Wylie is 312.9 miles (503.6 km) as the crow flies. Wylie is located NW of Opelousas. By car, the driving distance is approximately 375.5 miles, taking about 7h 33min. A direct flight would take roughly 1h 8min. Both are located in United States — Opelousas in Louisiana and Wylie in Texas.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Opelousas and Wylie. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.