Opelousas to Oxford, Mississippi: Road Trip Guide & Distance

How far is Opelousas from Oxford, Mississippi?

The distance from Opelousas to Oxford, Mississippi is 304 miles (489.3 km) as the crow flies. Oxford, Mississippi is located NNE of Opelousas. By car, the driving distance is approximately 380 miles, taking about 7h 39min. A direct flight would take roughly 1h 7min. Both are located in United States — Opelousas in Louisiana and Oxford, Mississippi in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Opelousas and Oxford, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.