New Orleans to Tupelo: Road Trip Guide & Distance

How far is New Orleans from Tupelo?

The distance from New Orleans to Tupelo is 308.1 miles (495.9 km) as the crow flies. Tupelo is located NNE of New Orleans. By car, the driving distance is approximately 385.2 miles, taking about 7h 45min. A direct flight would take roughly 1h 7min. Both are located in United States — New Orleans in Louisiana and Tupelo in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for New Orleans and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.