Nacogdoches to Odessa: Road Trip Guide & Distance

How far is Nacogdoches from Odessa?

The distance from Nacogdoches to Odessa is 453.5 miles (729.8 km) as the crow flies. Odessa is located W of Nacogdoches. By car, the driving distance is approximately 544.2 miles, taking about 10h 57min. A direct flight would take roughly 1h 25min. Both are located in United States.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Nacogdoches and Odessa. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.