Milwaukee to Sioux Falls: Road Trip Guide & Distance

How far is Milwaukee from Sioux Falls?

The distance from Milwaukee to Sioux Falls is 444.8 miles (715.8 km) as the crow flies. Sioux Falls is located W of Milwaukee. By car, the driving distance is approximately 503.2 miles, taking about 9h 7min. A direct flight would take roughly 1h 24min. Both are located in United States — Milwaukee in Wisconsin and Sioux Falls in South Dakota.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Milwaukee and Sioux Falls. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.