Melbourne, Florida to Myrtle Beach: Road Trip Guide & Distance

How far is Melbourne, Florida from Myrtle Beach?

The distance from Melbourne, Florida to Myrtle Beach is 400.5 miles (644.6 km) as the crow flies. Myrtle Beach is located NNE of Melbourne, Florida. By car, the driving distance is approximately 480.6 miles, taking about 9h 40min. A direct flight would take roughly 1h 18min. Both are located in United States — Melbourne, Florida in Florida and Myrtle Beach in South Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Melbourne, Florida and Myrtle Beach. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.