Mattoon to Saint Joseph: Road Trip Guide & Distance

How far is Mattoon from Saint Joseph?

The distance from Mattoon to Saint Joseph is 345 miles (555.2 km) as the crow flies. Saint Joseph is located W of Mattoon. By car, the driving distance is approximately 414 miles, taking about 8h 20min. A direct flight would take roughly 1h 12min. Both are located in United States — Mattoon in Illinois and Saint Joseph in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Mattoon and Saint Joseph. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.