Madisonville to Roanoke: Road Trip Guide & Distance

How far is Madisonville from Roanoke?

The distance from Madisonville to Roanoke is 415.3 miles (668.3 km) as the crow flies. Roanoke is located E of Madisonville. By car, the driving distance is approximately 498.3 miles, taking about 10h 2min. A direct flight would take roughly 1h 20min. Both are located in United States — Madisonville in Kentucky and Roanoke in Virginia.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Madisonville and Roanoke. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.