Louisville to Spartanburg: Road Trip Guide & Distance

How far is Louisville from Spartanburg?

The distance from Louisville to Spartanburg is 311.6 miles (501.5 km) as the crow flies. Spartanburg is located SE of Louisville. By car, the driving distance is approximately 398.7 miles, taking about 7h 57min. A direct flight would take roughly 1h 8min. Both are located in United States — Louisville in Kentucky and Spartanburg in South Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Louisville and Spartanburg. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.