Lexington, Kentucky to Winston-Salem: Road Trip Guide & Distance

How far is Lexington, Kentucky from Winston-Salem?

The distance from Lexington, Kentucky to Winston-Salem is 270.4 miles (435.1 km) as the crow flies. Winston-Salem is located ESE of Lexington, Kentucky. By car, the driving distance is approximately 338 miles, taking about 6h 48min. A direct flight would take roughly 1h 3min. Both are located in United States — Lexington, Kentucky in Kentucky and Winston-Salem in North Carolina.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Lexington, Kentucky and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.