Lexington, Kentucky to Sioux Falls: Road Trip Guide & Distance

How far is Lexington, Kentucky from Sioux Falls?

The distance from Lexington, Kentucky to Sioux Falls is 742.8 miles (1195.5 km) as the crow flies. Sioux Falls is located NW of Lexington, Kentucky. By car, the driving distance is approximately 891.4 miles, taking about 17h 56min. A direct flight would take roughly 2h 0min. Both are located in United States — Lexington, Kentucky in Kentucky and Sioux Falls in South Dakota.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Lexington, Kentucky and Sioux Falls. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.