Lexington, Kentucky to Myrtle Beach: Road Trip Guide & Distance

How far is Lexington, Kentucky from Myrtle Beach?

The distance from Lexington, Kentucky to Myrtle Beach is 435 miles (700 km) as the crow flies. Myrtle Beach is located SE of Lexington, Kentucky. By car, the driving distance is approximately 522 miles, taking about 10h 30min. A direct flight would take roughly 1h 23min. Both are located in United States — Lexington, Kentucky in Kentucky and Myrtle Beach in South Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Lexington, Kentucky and Myrtle Beach. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.