Lee's Summit to Tupelo: Road Trip Guide & Distance

How far is Lee's Summit from Tupelo?

The distance from Lee's Summit to Tupelo is 449.9 miles (724 km) as the crow flies. Tupelo is located SE of Lee's Summit. By car, the driving distance is approximately 539.8 miles, taking about 10h 52min. A direct flight would take roughly 1h 24min. Both are located in United States — Lee's Summit in Missouri and Tupelo in Mississippi.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Lee's Summit and Tupelo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.