Laredo to Odessa: Road Trip Guide & Distance

How far is Laredo from Odessa?

The distance from Laredo to Odessa is 345.5 miles (556 km) as the crow flies. Odessa is located NNW of Laredo. By car, the driving distance is approximately 414.6 miles, taking about 8h 20min. A direct flight would take roughly 1h 12min. Both are located in United States.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Laredo and Odessa. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.