Lancaster, Pennsylvania to Lexington, Kentucky: Road Trip Guide & Distance

How far is Lancaster, Pennsylvania from Lexington, Kentucky?

The distance from Lancaster, Pennsylvania to Lexington, Kentucky is 460.9 miles (741.7 km) as the crow flies. Lexington, Kentucky is located WSW of Lancaster, Pennsylvania. By car, the driving distance is approximately 553 miles, taking about 11h 8min. A direct flight would take roughly 1h 26min. Both are located in United States — Lancaster, Pennsylvania in Pennsylvania and Lexington, Kentucky in Kentucky.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Lancaster, Pennsylvania and Lexington, Kentucky. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.