La Crosse to Sedalia: Road Trip Guide & Distance

How far is La Crosse from Sedalia?

The distance from La Crosse to Sedalia is 367 miles (590.6 km) as the crow flies. Sedalia is located SSW of La Crosse. By car, the driving distance is approximately 440.4 miles, taking about 8h 52min. A direct flight would take roughly 1h 14min. Both are located in United States — La Crosse in Wisconsin and Sedalia in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for La Crosse and Sedalia. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.