La Crosse to Missoula: Road Trip Guide & Distance

How far is La Crosse from Missoula?

The distance from La Crosse to Missoula is 1121.5 miles (1804.8 km) as the crow flies. Missoula is located WNW of La Crosse. By car, the driving distance is approximately 1345.8 miles, taking about 27h 4min. A direct flight would take roughly 2h 45min. Both are located in United States — La Crosse in Wisconsin and Missoula in Montana.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for La Crosse and Missoula. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.