Knoxville to Wilmington, North Carolina: Road Trip Guide & Distance

How far is Knoxville from Wilmington, North Carolina?

The distance from Knoxville to Wilmington, North Carolina is 358.4 miles (576.8 km) as the crow flies. Wilmington, North Carolina is located ESE of Knoxville. By car, the driving distance is approximately 430.1 miles, taking about 8h 39min. A direct flight would take roughly 1h 13min. Both are located in United States — Knoxville in Tennessee and Wilmington, North Carolina in North Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Knoxville and Wilmington, North Carolina. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.