Knoxville to Wheeling, West Virginia: Road Trip Guide & Distance

How far is Knoxville from Wheeling, West Virginia?

The distance from Knoxville to Wheeling, West Virginia is 332.7 miles (535.4 km) as the crow flies. Wheeling, West Virginia is located NNE of Knoxville. By car, the driving distance is approximately 399.2 miles, taking about 8h 2min. A direct flight would take roughly 1h 10min. Both are located in United States — Knoxville in Tennessee and Wheeling, West Virginia in West Virginia.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Knoxville and Wheeling, West Virginia. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.