Knoxville to Tuscaloosa: Road Trip Guide & Distance

How far is Knoxville from Tuscaloosa?

The distance from Knoxville to Tuscaloosa is 281.4 miles (452.8 km) as the crow flies. Tuscaloosa is located SW of Knoxville. By car, the driving distance is approximately 351.7 miles, taking about 7h 5min. A direct flight would take roughly 1h 4min. Both are located in United States — Knoxville in Tennessee and Tuscaloosa in Alabama.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Knoxville and Tuscaloosa. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.