Knoxville to Muskogee: Road Trip Guide & Distance

How far is Knoxville from Muskogee?

The distance from Knoxville to Muskogee is 640.9 miles (1031.5 km) as the crow flies. Muskogee is located W of Knoxville. By car, the driving distance is approximately 769.1 miles, taking about 15h 28min. A direct flight would take roughly 1h 47min. Both are located in United States — Knoxville in Tennessee and Muskogee in Oklahoma.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Knoxville and Muskogee. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.