Knoxville to Memphis: Road Trip Guide & Distance

How far is Knoxville from Memphis?

The distance from Knoxville to Memphis is 349 miles (561.6 km) as the crow flies. Memphis is located W of Knoxville. By car, the driving distance is approximately 391.1 miles, taking about 7h 10min. A direct flight would take roughly 1h 12min. Both are located in United States.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Knoxville and Memphis. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.