Kirksville to St. Louis: Road Trip Guide & Distance

How far is Kirksville from St. Louis?

The distance from Kirksville to St. Louis is 167.1 miles (268.9 km) as the crow flies. St. Louis is located SE of Kirksville. By car, the driving distance is approximately 208.8 miles, taking about 4h 12min. A direct flight would take roughly 50min. Both are located in United States.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Kirksville and St. Louis. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.