Kirksville to Pueblo: Road Trip Guide & Distance

How far is Kirksville from Pueblo?

The distance from Kirksville to Pueblo is 656.9 miles (1057.2 km) as the crow flies. Pueblo is located W of Kirksville. By car, the driving distance is approximately 788.3 miles, taking about 15h 51min. A direct flight would take roughly 1h 49min. Both are located in United States — Kirksville in Missouri and Pueblo in Colorado.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Kirksville and Pueblo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.