Jacksonville Beach to Knoxville: Road Trip Guide & Distance

How far is Jacksonville Beach from Knoxville?

The distance from Jacksonville Beach to Knoxville is 417.9 miles (672.5 km) as the crow flies. Knoxville is located NNW of Jacksonville Beach. By car, the driving distance is approximately 501.4 miles, taking about 10h 5min. A direct flight would take roughly 1h 20min. Both are located in United States — Jacksonville Beach in Florida and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Jacksonville Beach and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.