Jackson, Tennessee to St. Louis: Road Trip Guide & Distance

How far is Jackson, Tennessee from St. Louis?

The distance from Jackson, Tennessee to St. Louis is 221.7 miles (356.8 km) as the crow flies. St. Louis is located NNW of Jackson, Tennessee. By car, the driving distance is approximately 277.1 miles, taking about 5h 35min. A direct flight would take roughly 57min. Both are located in United States — Jackson, Tennessee in Tennessee and St. Louis in Missouri.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Jackson, Tennessee and St. Louis. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.