Harrisonburg to Knoxville: Road Trip Guide & Distance

How far is Harrisonburg from Knoxville?

The distance from Harrisonburg to Knoxville is 326.8 miles (526 km) as the crow flies. Knoxville is located WSW of Harrisonburg. By car, the driving distance is approximately 392.2 miles, taking about 7h 53min. A direct flight would take roughly 1h 9min. Both are located in United States — Harrisonburg in Virginia and Knoxville in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Harrisonburg and Knoxville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.