Gulfport to Siesta Key: Road Trip Guide & Distance

How far is Gulfport from Siesta Key?

The distance from Gulfport to Siesta Key is 450.4 miles (724.8 km) as the crow flies. Siesta Key is located ESE of Gulfport. By car, the driving distance is approximately 540.5 miles, taking about 10h 52min. A direct flight would take roughly 1h 24min. Both are located in United States — Gulfport in Mississippi and Siesta Key in Florida.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Gulfport and Siesta Key. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.