Greenville, South Carolina to Joplin: Road Trip Guide & Distance

How far is Greenville, South Carolina from Joplin?

The distance from Greenville, South Carolina to Joplin is 694.5 miles (1117.7 km) as the crow flies. Joplin is located WNW of Greenville, South Carolina. By car, the driving distance is approximately 833.4 miles, taking about 16h 46min. A direct flight would take roughly 1h 54min. Both are located in United States — Greenville, South Carolina in South Carolina and Joplin in Missouri.

This is a serious multi-day road trip! We strongly recommend breaking this journey up with an overnight stay to ensure you arrive safely and refreshed. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. For a trip of this distance, flying is significantly faster. However, driving offers the flexibility to explore stops along the way.

Coordinates come from public place data for Greenville, South Carolina and Joplin. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.