Greenville, Mississippi to Opelousas: Road Trip Guide & Distance

How far is Greenville, Mississippi from Opelousas?

The distance from Greenville, Mississippi to Opelousas is 207.5 miles (333.9 km) as the crow flies. Opelousas is located SSW of Greenville, Mississippi. By car, the driving distance is approximately 259.4 miles, taking about 5h 13min. A direct flight would take roughly 55min. Both are located in United States — Greenville, Mississippi in Mississippi and Opelousas in Louisiana.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Greenville, Mississippi and Opelousas. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.