Greenville, Mississippi to Henderson, Kentucky: Road Trip Guide & Distance

How far is Greenville, Mississippi from Henderson, Kentucky?

The distance from Greenville, Mississippi to Henderson, Kentucky is 362.6 miles (583.6 km) as the crow flies. Henderson, Kentucky is located NNE of Greenville, Mississippi. By car, the driving distance is approximately 435.1 miles, taking about 8h 45min. A direct flight would take roughly 1h 14min. Both are located in United States — Greenville, Mississippi in Mississippi and Henderson, Kentucky in Kentucky.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Greenville, Mississippi and Henderson, Kentucky. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.