Grand Island to La Crosse: Road Trip Guide & Distance

How far is Grand Island from La Crosse?

The distance from Grand Island to La Crosse is 413.3 miles (665.1 km) as the crow flies. La Crosse is located ENE of Grand Island. By car, the driving distance is approximately 495.9 miles, taking about 9h 59min. A direct flight would take roughly 1h 20min. Both are located in United States — Grand Island in Nebraska and La Crosse in Wisconsin.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Grand Island and La Crosse. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.