Gainesville, Florida to Myrtle Beach: Road Trip Guide & Distance

344.5 miles 554.4 km · straight line
413.4 miles estimated 665.3 km · driving distance
8h 19min estimated drive time
$40 - $49 estimated fuel cost
~1h 12min flight time
35° NE bearing direction

How far is Gainesville, Florida from Myrtle Beach?

The distance from Gainesville, Florida to Myrtle Beach is 344.5 miles (554.4 km) as the crow flies. Myrtle Beach is located NE of Gainesville, Florida. By car, the driving distance is approximately 413.4 miles, taking about 8h 19min. A direct flight would take roughly 1h 12min. Both are located in United States — Gainesville, Florida in Florida and Myrtle Beach in South Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Gainesville, Florida and Myrtle Beach. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.

How to Get from Gainesville, Florida to Myrtle Beach

Method Time Est. Cost Best For
Drive 8h 19min $40 - $49 Flexible stops
Fly ~1h 12min $80–200* Speed
Bus ~9h 59min $33–$62* Budget
Train ~7h 54min $50–$145* Comfort

Suggested Stops Between Gainesville, Florida & Myrtle Beach

Quick Facts

Gainesville, Florida
29.65°N, 82.32°W
America/New_York
50m elevation
Myrtle Beach
33.69°N, 78.89°W
America/New_York
8m elevation
Explore more routes from Myrtle Beach

Did You Know?

  • At walking speed (3 mph), it would take about 115 hours of non-stop walking
  • By bicycle at 12 mph, the journey would take roughly 29 hours
  • You could travel this distance about 72.3 times to circle the Earth's equator
Data Sources & Estimate Notes GeoNames · OpenStreetMap · Driving distance estimated using road factor coefficients