Frederick to Louisville: Road Trip Guide & Distance

How far is Frederick from Louisville?

The distance from Frederick to Louisville is 456.2 miles (734.2 km) as the crow flies. Louisville is located W of Frederick. By car, the driving distance is approximately 560.9 miles, taking about 10h 18min. A direct flight would take roughly 1h 25min. Both are located in United States — Frederick in Maryland and Louisville in Kentucky.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Frederick and Louisville. The driving distance uses an OSRM road-route result when route data is available. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.