Fort Myers to Key Largo: Road Trip Guide & Distance

How far is Fort Myers from Key Largo?

The distance from Fort Myers to Key Largo is 139.2 miles (224 km) as the crow flies. Key Largo is located SE of Fort Myers. By car, the driving distance is approximately 174 miles, taking about 3h 30min. A direct flight would take roughly 47min. Both are located in United States.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Fort Myers and Key Largo. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.