Florence, South Carolina to Winston-Salem: Road Trip Guide & Distance

How far is Florence, South Carolina from Winston-Salem?

The distance from Florence, South Carolina to Winston-Salem is 134.3 miles (216.2 km) as the crow flies. Winston-Salem is located NNW of Florence, South Carolina. By car, the driving distance is approximately 168 miles, taking about 3h 23min. A direct flight would take roughly 46min. Both are located in United States — Florence, South Carolina in South Carolina and Winston-Salem in North Carolina.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Florence, South Carolina and Winston-Salem. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.