Florence, South Carolina to Smyrna: Road Trip Guide & Distance

How far is Florence, South Carolina from Smyrna?

The distance from Florence, South Carolina to Smyrna is 401.3 miles (645.9 km) as the crow flies. Smyrna is located WNW of Florence, South Carolina. By car, the driving distance is approximately 481.6 miles, taking about 9h 41min. A direct flight would take roughly 1h 18min. Both are located in United States — Florence, South Carolina in South Carolina and Smyrna in Tennessee.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Florence, South Carolina and Smyrna. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.