Florence, Alabama to Greenville, Mississippi: Road Trip Guide & Distance

How far is Florence, Alabama from Greenville, Mississippi?

The distance from Florence, Alabama to Greenville, Mississippi is 216.1 miles (347.7 km) as the crow flies. Greenville, Mississippi is located WSW of Florence, Alabama. By car, the driving distance is approximately 270 miles, taking about 5h 26min. A direct flight would take roughly 56min. Both are located in United States — Florence, Alabama in Alabama and Greenville, Mississippi in Mississippi.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Florence, Alabama and Greenville, Mississippi. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.