Fayetteville, Arkansas to Kirksville: Road Trip Guide & Distance

How far is Fayetteville, Arkansas from Kirksville?

The distance from Fayetteville, Arkansas to Kirksville is 298 miles (479.6 km) as the crow flies. Kirksville is located NNE of Fayetteville, Arkansas. By car, the driving distance is approximately 372.5 miles, taking about 7h 30min. A direct flight would take roughly 1h 6min. Both are located in United States — Fayetteville, Arkansas in Arkansas and Kirksville in Missouri.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Fayetteville, Arkansas and Kirksville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.