Enterprise to Spartanburg: Road Trip Guide & Distance

How far is Enterprise from Spartanburg?

The distance from Enterprise to Spartanburg is 338.5 miles (544.7 km) as the crow flies. Spartanburg is located NE of Enterprise. By car, the driving distance is approximately 406.1 miles, taking about 8h 10min. A direct flight would take roughly 1h 11min. Both are located in United States — Enterprise in Alabama and Spartanburg in South Carolina.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Heading East means you'll be driving into the sunrise if you start early. Keep your windshield clean for the best visibility.

Coordinates come from public place data for Enterprise and Spartanburg. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.