Edwardsville to Sikeston: Road Trip Guide & Distance

How far is Edwardsville from Sikeston?

The distance from Edwardsville to Sikeston is 135.1 miles (217.5 km) as the crow flies. Sikeston is located S of Edwardsville. By car, the driving distance is approximately 169 miles, taking about 3h 24min. A direct flight would take roughly 46min. Both are located in United States — Edwardsville in Illinois and Sikeston in Missouri.

For a drive of this length, it's recommended to plan at least one quick rest stop to stretch your legs and grab a coffee. Given the short distance, driving or taking a train is often faster and more convenient than dealing with airport security and flight boarding times.

Coordinates come from public place data for Edwardsville and Sikeston. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.