Durham, North Carolina to Zanesville: Road Trip Guide & Distance

How far is Durham, North Carolina from Zanesville?

The distance from Durham, North Carolina to Zanesville is 321.1 miles (516.7 km) as the crow flies. Zanesville is located NNW of Durham, North Carolina. By car, the driving distance is approximately 385.3 miles, taking about 7h 45min. A direct flight would take roughly 1h 9min. Both are located in United States — Durham, North Carolina in North Carolina and Zanesville in Ohio.

This is a solid day of driving. Be sure to take breaks every 2-3 hours to avoid driver fatigue, and plan your meals ahead of time. Since you'll be heading mostly West, pack a good pair of sunglasses if you plan to drive during the late afternoon to avoid the harsh sun glare.

Coordinates come from public place data for Durham, North Carolina and Zanesville. The driving distance is estimated from straight-line distance with a road-factor model, so confirm the route in your navigation app. Fuel, flight, bus, and train values are planning estimates and can change by date, provider, road closures, and border rules.